CEP290 抗体 (N-Term)
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北京 101111
Quick Overview for CEP290 抗体 (N-Term) (ABIN5514637)
抗原
See all CEP290 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- EQLCQDIIDY QKQIDSQKET LLSRRGEDSD YRSQLSKKNY ELIQYLDEIQ
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CEP290
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CEP290 (Centrosomal Protein 290kDa (CEP290))
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别名
- CEP290
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背景
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This gene encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer.
Alias Symbols: CT87, MKS4, POC3, rd16, BBS14, JBTS5, LCA10, NPHP6, SLSN6, 3H11Ag
Protein Size: 805 -
基因ID
- 80184
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NCBI登录号
- NM_025114, NP_079390
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UniProt
- Q05BJ6
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途径
- cAMP Metabolic Process, M Phase
抗原
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