Opiorphin Prepropeptide (OPRPN) (N-Term) 抗体
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北京 101111
Quick Overview for Opiorphin Prepropeptide (OPRPN) (N-Term) 抗体 (ABIN5514594)
抗原
适用
宿主
克隆类型
应用范围
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抗原表位
- N-Term
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原理
- OPRPN Antibody - N-terminal region
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序列
- SFNYTTPDYG HYDDKDTLDL NTPVDKTSNT LRVPDILALV IFAVVFLVGV
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human C5AR1
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP77605-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- Opiorphin Prepropeptide (OPRPN)
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别名
- OPRPN
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背景
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Background Information: This gene encodes a member of the proline-rich protein family. The encoded protein has multiple proposed functions, including roles in pain suppression, penile erection, and protection of the eye surface. The QRFSR pentapeptide, known as opiorphin, is derived from the N-terminal of this protein. Opiorphin inhibits the enkephalin-inactivating peptidases neprilysin and aminopeptidase N, and this activity is thought to reduce sensitivity to painful stimuli by effecting enkephalin-related activation of opioid-dependent pathways. Opiorphin may also act as an anti-depressant. Alternative splicing results in multiple transcript variants.
Gene Name: opiorphin prepropeptide
Alternative Symbols: BPLP, PRL1, PROL1, opiorphin
Protein Name: opiorphin prepropeptide
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分子量
- 38 kDa
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基因ID
- 58503
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NCBI登录号
- NP_001727
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UniProt
- P21730
抗原
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