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RITA1 抗体 (C-Term)

RITA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5514467
发货至: 中国
  • 抗原 See all RITA1 products
    RITA1 (Tyrosine-Based Site-Specific Recombinase (Recombinase Triad in CMGI-2) (RITA1))
    抗原表位
    C-Term
    适用
    宿主
    • 1
    克隆类型
    • 1
    多克隆
    标记
    • 1
    This RITA1 antibody is un-conjugated
    应用范围
    • 1
    • 1
    Western Blotting (WB)
    序列
    TNGPQDLRPS TSGVTFRSPL VTSRARSVSI SVPSTPRRGG ATQKPKPPWK
    产品特性
    This is a rabbit polyclonal antibody against RITA1. It was validated on Western Blot.
    纯化方法
    Affinity purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C-terminal region of Human RITA1
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    RITA1 (Tyrosine-Based Site-Specific Recombinase (Recombinase Triad in CMGI-2) (RITA1))
    别名
    RITA1 (RITA1 产品)
    别名
    AI853657 antibody, C86297 antibody, Rita antibody, RBPJ interacting and tubulin associated 1 antibody, Rita1 antibody
    背景
    RITA1 is a tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. It shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. And it may play a role in neurogenesis.

    Alias Symbols: C12orf52, RITA, PSEC0043

    Protein Size: 269
    基因ID
    84934
    NCBI登录号
    XP_005254029
    UniProt
    Q96K30
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