Optimal working dilution should be determined by the investigator.
限制
仅限研究用
状态
Liquid
缓冲液
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
抗原
RITA1
(Tyrosine-Based Site-Specific Recombinase (Recombinase Triad in CMGI-2) (RITA1))
别名
RITA1
背景
RITA1 is a tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. It shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. And it may play a role in neurogenesis.