MARCH8 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for MARCH8 抗体 (N-Term) (ABIN5514406)
抗原
See all MARCH8 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
原理
- MARCH8 Antibody - N-terminal region
-
序列
- MSMPLHQISA IPSQDAISAR VYRSKTKEKE REEQNEKTLG HFMSHSSNIS
-
产品特性
- This is a rabbit polyclonal antibody against MARH8. It was validated on Western Blot.
-
纯化方法
- Affinity purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human MARH8
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP75860-100UG
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- prevent freeze-thaw cycles
-
储存条件
- 4 °C,-20 °C
-
储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- MARCH8 (Membrane-Associated Ring Finger (C3HC4) 8, E3 Ubiquitin Protein Ligase (MARCH8))
-
别名
- MARCH8
-
背景
-
Background Information: MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al., 2003 [PubMed 12582153], Bartee et al., 2004 [PubMed 14722266]).[supplied by OMIM, Apr 2010]
Gene Name: membrane associated ring-CH-type finger 8
Alternative Symbols: MIR, CMIR, c-MIR, MARCH8, RNF178, MARCH-VIII
Protein Name: E3 ubiquitin-protein ligase MARCH8
-
分子量
- 32kDa
-
基因ID
- 220972
-
UniProt
- Q5T0T0
抗原
-