PFKFB3 抗体 (C-Term)
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北京 101111
Quick Overview for PFKFB3 抗体 (C-Term) (ABIN5514397)
抗原
See all PFKFB3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- PFKFB3 Antibody - C-terminal region
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序列
- VESVCTHRER SEDAKKGPNP LMRRNSVTPL ASPEPTKKPR INSFEEHVAS
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预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against F263. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human F263
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anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3) (AA 400-500) antibody
PFKFB3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3) (AA 412-520) antibodyPFKFB3 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3F3 unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3) (AA 454-484), (C-Term) antibodyPFKFB3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB04030 unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3) antibodyKD Validated PFKFB3 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB4880 unconjugated Recombinant Antibody
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3) (AA 1-520) antibodyPFKFB3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3) (AA 454-484) antibodyPFKFB3 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3) (C-Term) antibodyPFKFB3 适用: 人 WB, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3) (pSer467) antibodyPFKFB3 适用: 人 WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3) (AA 401-520) antibodyPFKFB3 适用: 人 WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3) (C-Term) antibodyPFKFB3 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56582-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- PFKFB3 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3))
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别名
- PFKFB3
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背景
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Background Information: The protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate (F2,6BP), and a fructose-2,6-biphosphatase activity that catalyzes the degradation of F2,6BP. This protein is required for cell cycle progression and prevention of apoptosis. It functions as a regulator of cyclin-dependent kinase 1, linking glucose metabolism to cell proliferation and survival in tumor cells. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
Alternative Symbols: PFK2, IPFK2, iPFK-2
Protein Name: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
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分子量
- 57kDa
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基因ID
- 5209
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UniProt
- Q16875
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途径
- AMPK Signaling, Regulation of Carbohydrate Metabolic Process
抗原
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