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LARP6 抗体 (AA 1-491)

LARP6 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
产品编号 ABIN527496
发货至: 中国
  • 抗原 See all LARP6 抗体
    LARP6 (La Ribonucleoprotein Domain Family, Member 6 (LARP6))
    抗原表位
    • 8
    • 8
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    AA 1-491
    适用
    • 27
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 26
    • 1
    小鼠
    克隆类型
    • 27
    多克隆
    标记
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    This LARP6 antibody is un-conjugated
    应用范围
    • 21
    • 17
    • 14
    • 14
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    原理
    Mouse polyclonal antibody raised against a full-length human LARP6 protein.
    序列
    MAQSGGEARP GPKTAVQIRV AIQEAEDVDE LEDEEEGAET RGAGDPARYL SPGWGSASEE EPSRGHSGTT ASGGENERED LEQEWKPPDE ELIKKLVDQI EFYFSDENLE KDAFLLKHVR RNKLGYVSVK LLTSFKKVKH LTRDWRTTAH ALKYSVVLEL NEDHRKVRRT TPVPLFPNEN LPSKMLLVYD LYLSPKLWAL ATPQKNGRVQ EKVMEHLLKL FGTFGVISSV RILKPGRELP PDIRRISSRY SQVGTQECAI VEFEEVEAAI KAHEFMITES QGKENMKAVL IGMKPPKKKP AKDKNHDEEP TASIHLNKSL NKRVEELQYM GDESSANSSS DPESNPTSPM AGRRHAATNK LSPSGHQNLF LSPNASPCTS PWSSPLAQRK GVSRKSPLAE EGRLNCSTSP EIFRKCMDYS SDSSVTPSGS PWVRRRRQAE MGTQEKSPGT SPLLSRKMQT ADGLPVGVLR LPRGPDNTRG FHGHERSRAC V
    交叉反应
    产品特性
    Antibody reactive against mammalian transfected lysate.
    免疫原
    LARP6 (NP_060827, 1 a.a. ~ 491 a.a) full-length human protein.
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    In 1x PBS, pH 7.4
    注意事项
    Aliquot to avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Blackstock, Higashi, Sukhanov, Shai, Stefanovic, Tabony, Yoshida, Delafontaine: "Insulin-like growth factor-1 increases synthesis of collagen type I via induction of the mRNA-binding protein LARP6 expression and binding to the 5' stem-loop of COL1a1 and COL1a2 mRNA." in: The Journal of biological chemistry, Vol. 289, Issue 11, pp. 7264-74, (2014) (PubMed).

    Wang, Stefanovic: "Role of LARP6 and nonmuscle myosin in partitioning of collagen mRNAs to the ER membrane." in: PLoS ONE, Vol. 9, Issue 10, pp. e108870, (2014) (PubMed).

    Manojlovic, Blackmon, Stefanovic: "Tacrolimus (FK506) prevents early stages of ethanol induced hepatic fibrosis by targeting LARP6 dependent mechanism of collagen synthesis." in: PLoS ONE, Vol. 8, Issue 6, pp. e65897, (2013) (PubMed).

    Vukmirovic, Manojlovic, Stefanovic: "Serine-threonine kinase receptor-associated protein (STRAP) regulates translation of type I collagen mRNAs." in: Molecular and cellular biology, Vol. 33, Issue 19, pp. 3893-906, (2013) (PubMed).

    Manojlovic, Stefanovic: "A novel role of RNA helicase A in regulation of translation of type I collagen mRNAs." in: RNA (New York, N.Y.), Vol. 18, Issue 2, pp. 321-34, (2012) (PubMed).

    Challa, Stefanovic: "A novel role of vimentin filaments: binding and stabilization of collagen mRNAs." in: Molecular and cellular biology, Vol. 31, Issue 18, pp. 3773-89, (2011) (PubMed).

    Cai, Fritz, Stefanovic, Stefanovic: "Binding of LARP6 to the conserved 5' stem-loop regulates translation of mRNAs encoding type I collagen." in: Journal of molecular biology, Vol. 395, Issue 2, pp. 309-26, (2010) (PubMed).

    Cai, Fritz, Stefanovic, Stefanovic: "Nonmuscle myosin-dependent synthesis of type I collagen." in: Journal of molecular biology, Vol. 401, Issue 4, pp. 564-78, (2010) (PubMed).

  • 抗原
    LARP6 (La Ribonucleoprotein Domain Family, Member 6 (LARP6))
    别名
    LARP6 (LARP6 产品)
    别名
    im:7142825 antibody, wu:fa55b04 antibody, ACHN antibody, 5430431G03Rik antibody, AI552438 antibody, Achn antibody, RGD1308414 antibody, La ribonucleoprotein domain family, member 6b antibody, La ribonucleoprotein domain family member 6 antibody, La ribonucleoprotein domain family, member 6 antibody, larp6b antibody, LARP6 antibody, Larp6 antibody
    背景
    Full Gene Name: La ribonucleoprotein domain family, member 6
    Synonyms: ACHN,FLJ11196
    基因ID
    55323
    NCBI登录号
    NM_018357
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