B3GAT3 抗体 (AA 1-335)
Quick Overview for B3GAT3 抗体 (AA 1-335) (ABIN525639)
抗原
See all B3GAT3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-335
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原理
- Mouse polyclonal antibody raised against a full-length human B3GAT3 protein.
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序列
- MKLKLKNVFL AYFLVSIAGL LYALVQLGQP CDCLPPLRAA AEQLRQKDLR ISQLQAELRR PPPAPAQPPE PEALPTIYVV TPTYARLVQK AELVRLSQTL SLVPRLHWLL VEDAEGPTPL VSGLLAASGL LFTHLVVLTP KAQRLREGEP GWVHPRGVEQ RNKALDWLRG RGGAVGGEKD PPPPGTQGVV YFADDDNTYS RELFEEMRWT RGVSVWPVGL VGGLRFEGPQ VQDGRVVGFH TAWEPSRPFP VDMAGFAVAL PLLLDKPNAQ FDSTAPRGHL ESSLLSHLVD PKDLEPRAAN CTRVLVWHTR TEKPKMKQEE QLQRQGRGSD PAIEV
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交叉反应
- 人
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产品特性
- Antibody reactive against mammalian transfected lysate.
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免疫原
- B3GAT3 (NP_036332.2, 1 a.a. ~ 335 a.a) full-length human protein.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- In 1x PBS, pH 7.4
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注意事项
- Aliquot to avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Functional validation of novel compound heterozygous variants in B3GAT3 resulting in severe osteopenia and fractures: expanding the disease phenotype." in: BMC medical genetics, Vol. 17, Issue 1, pp. 86, (2016) (PubMed).
: "Skeletal dysplasia in a consanguineous clan from the island of Nias/Indonesia is caused by a novel mutation in B3GAT3." in: Human genetics, Vol. 134, Issue 7, pp. 691-704, (2015) (PubMed).
: "Faulty initiation of proteoglycan synthesis causes cardiac and joint defects. ..." in: American journal of human genetics, Vol. 89, Issue 1, pp. 15-27, (2011) (PubMed).
: "Activation of TonEBP by calcium controls {beta}1,3-glucuronosyltransferase-I expression, a key regulator of glycosaminoglycan synthesis in cells of the intervertebral disc." in: The Journal of biological chemistry, Vol. 284, Issue 15, pp. 9824-34, (2009) (PubMed).
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Functional validation of novel compound heterozygous variants in B3GAT3 resulting in severe osteopenia and fractures: expanding the disease phenotype." in: BMC medical genetics, Vol. 17, Issue 1, pp. 86, (2016) (PubMed).
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- B3GAT3 (beta-1,3-Glucuronyltransferase 3 (Glucuronosyltransferase I) (B3GAT3))
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别名
- B3GAT3
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背景
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Full Gene Name: beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
Synonyms: GLCATI,GlcAT-I -
基因ID
- 26229
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NCBI登录号
- NM_012200
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途径
- Glycosaminoglycan Metabolic Process
抗原
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