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AIM2 抗体 (AA 1-343)

This anti-AIM2 antibody is a 小鼠 多克隆 antibody detecting AIM2 in WB 和 IF. Suitable for 人. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN522906
发货至: 中国

Quick Overview for AIM2 抗体 (AA 1-343) (ABIN522906)

抗原

See all AIM2 抗体
AIM2 (Absent in Melanoma 2 (AIM2))

适用

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宿主

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小鼠

克隆类型

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多克隆

标记

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This AIM2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    AA 1-343

    原理

    Mouse polyclonal antibody raised against a full-length human AIM2 protein.

    序列

    MESKYKEILL LTGLDNITDE ELDRFKFFLS DEFNIATGKL HTANRIQVAT LMIQNAGAVS AVMKTIRIFQ KLNYMLLAKR LQEEKEKVDK QYKSVTKPKP LSQAEMSPAA SAAIRNDVAK QRAAPKVSPH VKPEQKQMVA QQESIREGFQ KRCLPVMVLK AKKPFTFETQ EGKQEMFHAT VATEKEFFFV KVFNTLLKDK FIPKRIIIIA RYYRHSGFLE VNSASRVLDA ESDQKVNVPL NIIRKAGETP KINTLQTQPL GTIVNGLFVV QKVTEKKKNI LFDLSDNTGK MEVLGVRNED TMKCKEGDKV RLTFFTLSKN GEKLQLTSGV HSTIKVIKAK KKT

    交叉反应

    产品特性

    Antibody reactive against mammalian transfected lysate.

    免疫原

    AIM2 (NP_004824, 1 a.a. ~ 343 a.a) full-length human protein.
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    In 1x PBS, pH 7.4

    注意事项

    Aliquot to avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Ansari, Singh, Dutta, Veettil, Dutta, Chikoti, Lu, Everly, Chandran: "Constitutive interferon-inducible protein 16-inflammasome activation during Epstein-Barr virus latency I, II, and III in B and epithelial cells." in: Journal of virology, Vol. 87, Issue 15, pp. 8606-23, (2013) (PubMed).

    Lee, Li, Gretz, Gebert, Dihlmann: "Absent in Melanoma 2 (AIM2) is an important mediator of interferon-dependent and -independent HLA-DRA and HLA-DRB gene expression in colorectal cancers." in: Oncogene, Vol. 31, Issue 10, pp. 1242-53, (2012) (PubMed).

    Wang, Hsu, Chen, Liang, Chen, Ojcius, Tsang, Hsueh, Wu, Chang: "Interactome-wide analysis identifies end-binding protein 1 as a crucial component for the speck-like particle formation of activated absence in melanoma 2 (AIM2) inflammasomes." in: Molecular & cellular proteomics : MCP, Vol. 11, Issue 11, pp. 1230-44, (2012) (PubMed).

    Fernandes-Alnemri, Yu, Datta, Wu, Alnemri: "AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA." in: Nature, Vol. 458, Issue 7237, pp. 509-13, (2009) (PubMed).

  • 抗原

    AIM2 (Absent in Melanoma 2 (AIM2))

    别名

    AIM2

    背景

    Full Gene Name: absent in melanoma 2
    Synonyms: PYHIN4

    基因ID

    9447

    NCBI登录号

    NM_004833

    途径

    Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
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