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AADAC 抗体 (AA 201-300)

This anti-AADAC antibody is a 小鼠 单克隆 antibody detecting AADAC in WB 和 ELISA. Suitable for 人. This Primary Antibody has been cited in 5+ publications.
产品编号 ABIN513029
发货至: 中国

Quick Overview for AADAC 抗体 (AA 201-300) (ABIN513029)

抗原

See all AADAC 抗体
AADAC (Arylacetamide Deacetylase (Esterase) (AADAC))

适用

  • 24
  • 17
  • 16
  • 4
  • 2
  • 2
  • 2
  • 1

宿主

  • 38
  • 1
小鼠

克隆类型

  • 39
单克隆

标记

  • 15
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This AADAC antibody is un-conjugated

应用范围

  • 27
  • 13
  • 13
  • 11
  • 5
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA

克隆位点

2E8
  • 抗原表位

    • 15
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-300

    原理

    Mouse monoclonal antibody raised against a partial recombinant AADAC.

    序列

    QLLDDPDVKI KLKIQSLIYP ALQPLDVDLP SYQENSNFLF LSKSLMVRFW SEYFTTDRSL EKAMLSRQHV PVESSHLFKF INWSSLLPER FIKGHVYNNP

    交叉反应

    产品特性

    Antibody Reactive Against Recombinant Protein.

    免疫原

    AADAC (NP_001077, 201 a.a. ~ 300 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    亚型

    IgG2b
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    In 1x PBS, pH 7.4

    注意事项

    Aliquot to avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Muta, Fukami, Nakajima, Yokoi: "N-Glycosylation during translation is essential for human arylacetamide deacetylase enzyme activity." in: Biochemical pharmacology, Vol. 87, Issue 2, pp. 352-9, (2014) (PubMed).

    Kobayashi, Fukami, Nakajima, Watanabe, Nakajima, Yokoi: "Species differences in tissue distribution and enzyme activities of arylacetamide deacetylase in human, rat, and mouse." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 40, Issue 4, pp. 671-9, (2012) (PubMed).

    Shimizu, Fukami, Kobayashi, Takamiya, Aoki, Nakajima, Yokoi: "A novel polymorphic allele of human arylacetamide deacetylase leads to decreased enzyme activity." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 40, Issue 6, pp. 1183-90, (2012) (PubMed).

    Kobayashi, Fukami, Higuchi, Nakajima, Yokoi: "Metabolic activation by human arylacetamide deacetylase, CYP2E1, and CYP1A2 causes phenacetin-induced methemoglobinemia." in: Biochemical pharmacology, Vol. 84, Issue 9, pp. 1196-206, (2012) (PubMed).

    Watanabe, Fukami, Nakajima, Takamiya, Aoki, Yokoi: "Human arylacetamide deacetylase is a principal enzyme in flutamide hydrolysis." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 37, Issue 7, pp. 1513-20, (2009) (PubMed).

  • 抗原

    AADAC (Arylacetamide Deacetylase (Esterase) (AADAC))

    别名

    AADAC

    背景

    Full Gene Name: arylacetamide deacetylase (esterase)
    Synonyms: CES5A1,DAC

    基因ID

    13

    NCBI登录号

    NM_001086
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