VCAM1 抗体 (PE)
(2 references)Quick Overview for VCAM1 抗体 (PE) (ABIN509567)
抗原
See all VCAM1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD106 PE
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特异性
- The mouse monoclonal antibody STA recognizes an extracellular epitope of CD106 antigen (VCAM-1), a 100-110 kDa type I membrane protein of the immunoglobulin superfamily, a crucial mediator of leukocyte adhesion, and a costimulation molecule.
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交叉反应 （详细）
- Human
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纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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免疫原
- Human DS6 T cell line
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亚型
- IgG1
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anti-Vascular Cell Adhesion Molecule 1 (VCAM1) (AA 1-739) antibody
VCAM1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Vascular Cell Adhesion Molecule 1 (VCAM1) (AA 1-739) antibodyVCAM1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Vascular Cell Adhesion Molecule 1 (VCAM1) antibodyVCAM1 适用: 人, 犬, 猴 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 3H10 unconjugated
anti-Vascular Cell Adhesion Molecule 1 (VCAM1) (AA 25-183) antibodyVCAM1 适用: 人, 大鼠, 猴 WB, FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 6A11D8 unconjugated
anti-Vascular Cell Adhesion Molecule 1 (VCAM1) (AA 109-318) antibodyVCAM1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vascular Cell Adhesion Molecule 1 (VCAM1) (AA 300-400) antibodyVCAM1 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Vascular Cell Adhesion Molecule 1 (VCAM1) antibodyVCAM1 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 6G9 unconjugated
anti-Vascular Cell Adhesion Molecule 1 (VCAM1) (AA 511-682) antibodyVCAM1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vascular Cell Adhesion Molecule 1 (VCAM1) (AA 369-658) antibodyVCAM1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vascular Cell Adhesion Molecule 1 (VCAM1) (AA 409-682) antibodyVCAM1 适用: 兔 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 3-2# unconjugated
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应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
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限制
- 仅限研究用
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溶解方式
- No reconstitution is necessary.
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缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
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Do not freeze.
Avoid prolonged exposure to light. -
储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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: "Modeling the early events of severe acute respiratory syndrome coronavirus infection in vitro." in: Journal of virology, Vol. 80, Issue 6, pp. 2684-93, (2006) (PubMed).
: "Expression of VCAM-1 (CD106) by a subset of TCR gamma delta-bearing lymphocyte clones. Involvement of a metalloprotease in the specific hydrolytic release of the soluble isoform." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 154, Issue 3, pp. 1069-77, (1995) (PubMed).
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: "Modeling the early events of severe acute respiratory syndrome coronavirus infection in vitro." in: Journal of virology, Vol. 80, Issue 6, pp. 2684-93, (2006) (PubMed).
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- VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
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别名
- CD106
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背景
- Vascular cell adhesion molecule 1,CD106 / VCAM-1 (vascular cell adhesion molecule-1) is an Ig-like cell surface adhesion molecule binding VLA-4 integrin. VCAM-1 is a potent T cell costimulatory molecule taking part in their positive selection and survival, as well as in adhesion, transendothelial migration and activation of peripheral T cells. VCAM-1 is also involved in endothelial cell-cell contacts. Whereas VCAM-1 normally mediates leukocyte extravasion to sites of tissue inflammation, tumour cells can use overexpressed VCAM-1 to escape T cell immunity. Soluble form of VCAM-1 (sVCAM-1) is an inflammatory marker and can be used also in prognosis of subsequent cariovascular events following acute coronary syndromes.,VCAM-1, INCAM-100
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基因ID
- 7412
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UniProt
- P19320
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途径
- Carbohydrate Homeostasis
抗原
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