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CD86 抗体

This anti-CD86 antibody is a 小鼠 单克隆 antibody detecting CD86 in FACS. Suitable for 人, Cynomolgus, Baboon 和 猕猴.
产品编号 ABIN5067873
发货至: 中国

Quick Overview for CD86 抗体 (ABIN5067873)

抗原

See all CD86 抗体
CD86

适用

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人, Cynomolgus, Baboon, 猕猴

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD86 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

质量等级

GMP Grade

克隆位点

BU63
  • 原理

    CD86 Unconjugated Antibody

    产品特性

    BU63 recognizes ~70Kda a surface antigen protein of Ig superfamily characterized as CD86 expressed by most antigen presenting cells (APC). Depending on the immunological condition, CD86 specifically binds with its two ligands CD28 and CD152 (CTLA-4) expressed by T cells. Binding with CD28, CD86 provides stimulatory signal and activates T cells whereas binding with CD152 (CTLA-4) CD86 provides inhibitory signal to T cells. Generally, high-level CD86 expression was noticed on peripheral monocytes, tissue macrophages and dendritic cells, and also on activated B cells. CD86 is useful in the clinical diagnosis of cancer cells including malignant Hodgkin's and non-hodgkin's diseases.

    纯化方法

    Purified

    纯度

    >95 %

    免疫原

    B-lymphoblastoid cell line ARH 77

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C
  • 抗原

    CD86

    别名

    CD86

    UniProt

    P42081

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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