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Malondialdehyde 抗体

MDA WB, ELISA, ICC, IF, FACS 宿主: 小鼠 Monoclonal 6H6 unconjugated
产品编号 ABIN5067343
发货至: 中国
  • 抗原 See all Malondialdehyde (MDA) 抗体
    Malondialdehyde (MDA)
    适用
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    宿主
    • 25
    • 2
    • 1
    小鼠
    克隆类型
    • 25
    • 3
    单克隆
    标记
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Malondialdehyde antibody is un-conjugated
    应用范围
    • 26
    • 24
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    • 14
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    • 2
    • 1
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    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)
    特异性
    Specific for MDA conjugated proteins. Does not detect free MDA. Does not cross-react with Acrolein, Crotonaldehyde, Hexanoyl Lysine, 4-HHE, 4-HNE, or Methylglyoxal modified proteins.
    纯化方法
    Protein G Purified
    免疫原
    Synthetic Malondialdehyde modified Keyhole Limpet Hemocyanin (KLH).
    克隆位点
    6H6
    亚型
    IgG1
    Top Product
    Discover our top product MDA Primary Antibody
  • 应用备注
    • WB (1:1000)
    • ICC/IF (1:50)
    • FACS (1:50)
    • FCM (1:50)
    • ELISA (1:1000)
    • optimal dilutions for assays should be determined by the user.
    说明

    A 1:1000 dilution of ABIN5067343 was sufficient for detection of Malondialdehyde in 2 μg of Malondialdehyde conjugated to BSA by ECL immunoblot analysis using Goat Anti-Mouse IgG:HRP as the secondary Antibody.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS pH 7.4, 50 % glycerol, 0.09 % Sodium azide, Storage buffer may change when conjugated
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C
  • 抗原
    Malondialdehyde (MDA)
    别名
    Malondialdehyde (MDA 产品)
    物质类
    Chemical
    背景
    Malondialdehyde (MDA) is the biomarker in greatest diagnostic use, due to its molecular stability. This three-carbon, low-molecular weight aldehyde has a strong affinity for amino acids, which results in adduct formation to both free amino acids and proteins. Increased MDA levels have been found at correlating levels in breast cancer, and lung cancer patients. Other diseased states with elevated MDA levels include diabetes and Alzheimer's disease. Multiple laboratory techniques exist for quantification of MDA levels, including the thiobarbituric acid reactive substances (TBARS) assay. In addition to use as a biomarker, MDA has been shown to have mutagenic effects on tissues themselves as adduct formation can result in DNA cross-linking.
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