FNIP1 抗体 (HRP)
Quick Overview for FNIP1 抗体 (HRP) (ABIN5066852)
抗原
See all FNIP1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Strong expression is found in the heart, liver placenta, muscle, nasal mucosa, salivary gland and uvula and moderate expression in kidney and lung. Higher levels detected in clear cell renal cell carcinoma (RCC) and chromophobe RCC than in normal kidney tissue.,Detects ~130 kDa.
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Peptide Affinity Purified
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免疫原
- Synthetic peptide from the mid-protein of Human FNIP1
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亚型
- IgG
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anti-Folliculin Interacting Protein 1 (FNIP1) antibody
FNIP1 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Folliculin Interacting Protein 1 (FNIP1) antibody (FITC)FNIP1 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal FITC
anti-Folliculin Interacting Protein 1 (FNIP1) antibody (Biotin)FNIP1 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal Biotin
anti-Folliculin Interacting Protein 1 (FNIP1) antibody (PE)FNIP1 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal PE
anti-Folliculin Interacting Protein 1 (FNIP1) antibody (PerCP)FNIP1 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal PerCP
anti-Folliculin Interacting Protein 1 (FNIP1) antibody (APC)FNIP1 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal APC
anti-Folliculin Interacting Protein 1 (FNIP1) antibody (Atto 488)FNIP1 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal Atto 488
anti-Folliculin Interacting Protein 1 (FNIP1) antibody (Atto 594)FNIP1 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal Atto 594
anti-Folliculin Interacting Protein 1 (FNIP1) antibody (Atto 390)FNIP1 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal Atto 390
anti-Folliculin Interacting Protein 1 (FNIP1) (AA 221-508) antibodyFNIP1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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- WB (1:1000)
- ICC/IF (1:100)
- IHC (1:50)
- optimal dilutions for assays should be determined by the user.
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说明
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A 1:1000 dilution of ABIN5066852 was sufficient for detection of FNIP1 in 15 μg of mouse kidney cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Conjugated antibodies should be stored at 4°C
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- FNIP1 (Folliculin Interacting Protein 1 (FNIP1))
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别名
- FNIP1
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背景
- Folliculin-interacting protein 1 (FNIP1) is a co-chaperone of HSP90 (1). It Inhibits the ATPase activity of HSP90AA1 leading to reduction in its chaperone activity. It may be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways and may regulate the phosphorylation of RPS6KB1 (2). FNIP1 is strongly expressed in the heart, liver placenta, muscle, nasal mucosa, salivary gland, and uvula. Elevated levels of FNIP1 have been detected in renal cell carcinoma (RCC) (3).
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基因ID
- 96459
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NCBI登录号
- NP_001008738
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UniProt
- Q8TF40
抗原
-
