Fibrillarin/Nop1p Nucleolar Marker 抗体
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北京 101111
Quick Overview for Fibrillarin/Nop1p Nucleolar Marker 抗体 (ABIN504711)
抗原
适用
宿主
克隆类型
应用范围
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交叉反应
- Caenorhabditis elegans (C. elegans), Fruit Fly (Drosophila melanogaster), 人, 小鼠
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纯化方法
- Purified
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免疫原
- Mice were injected with yeast nuclear preparations and hybridomas were screened by immunofluorescence on yeast cells and by western blotting on yeast protein homogenates.
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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储存条件
- -20 °C
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- Fibrillarin/Nop1p Nucleolar Marker
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背景
- The Nop1p protein is 327 amino acids in size (34. 5 kDa), is essential for yeast viability, and is localized in the nucleoli (1). The systematic name for S. cerevisiae Nop1 is YDL014W, and it is now known to be part of the small subunit processome complex, involved in the processing of pre-18S ribosomal RNA. Nop1p is the yeast homologue of a protein apparently found in all eukaryotes and archea generally called fibrillarin. Fibrillarin/Nop1p is extraordinarily conserved, so that the yeast and human proteins are 67% identical, and the human protein can functionally replace the yeast protein.
抗原
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