电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

TXNIP 抗体 (AA 50-300)

TXNIP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5027615
发货至: 中国
  • 抗原 See all TXNIP 抗体
    TXNIP (Thioredoxin Interacting Protein (TXNIP))
    抗原表位
    • 16
    • 14
    • 9
    • 8
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 50-300
    适用
    • 61
    • 47
    • 32
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    宿主
    • 70
    • 5
    克隆类型
    • 62
    • 13
    多克隆
    标记
    • 30
    • 8
    • 7
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TXNIP antibody is un-conjugated
    应用范围
    • 57
    • 32
    • 15
    • 14
    • 14
    • 8
    • 8
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Protein A Chromatography
    免疫原
    A partial length recombinant TxNIP protein (amino acids 50-300) was used as the immunogen for this antibody.
    亚型
    IgG
    Top Product
    Discover our top product TXNIP Primary Antibody
  • 应用备注
    WB: 1-3 μg/mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 0.05 % BSA, PH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原
    TXNIP (Thioredoxin Interacting Protein (TXNIP))
    别名
    TxNIP/VDUP1 (TXNIP 产品)
    别名
    EST01027 antibody, HHCPA78 antibody, THIF antibody, VDUP1 antibody, Gm348 antibody, Trf3 antibody, TBP2 antibody, TRF3 antibody, 1200008J08Rik antibody, AA682105 antibody, Hyplip1 antibody, Tbp-2 antibody, Vdup1 antibody, sb:cb368 antibody, txnip antibody, thioredoxin interacting protein antibody, TATA box binding protein like 2 antibody, TATA-box binding protein like 2 antibody, thioredoxin interacting protein L homeolog antibody, thioredoxin interacting protein a antibody, TXNIP antibody, Tbpl2 antibody, TBPL2 antibody, Txnip antibody, txnip.L antibody, txnip antibody, txnipa antibody
    背景
    TXNIP (thioredoxin interacting protein) inhibits thioredoxin activity by limiting its bioavailability in response to oxidative stress. TXNIP restores COPS5-induced suppression of CDKN1B stability by interacting with COPS5 and blocks the COPS5-mediated translocation of CDKN1B from nucleus to the cytoplasm. TXNIP functions as a transcriptional repressor. TXNIP has been reported to be a suppressor of tumor cell growth and inhibits the proteasomal degradation of DDIT4, contributing to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1). TXNIP is expresed in adipose tissue, adrenal cortex, adrenal gland, amniotic fluid and amygdale.
    分子量
    44 kDa
    基因ID
    10628
    UniProt
    Q9H3M7
    途径
    Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome
You are here:
客服