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TXNIP 抗体 (AA 50-300)

This anti-TXNIP antibody is a 兔 多克隆 antibody detecting TXNIP in WB. Suitable for 人.
产品编号 ABIN5027615
发货至: 中国

Quick Overview for TXNIP 抗体 (AA 50-300) (ABIN5027615)

抗原

See all TXNIP 抗体
TXNIP (Thioredoxin Interacting Protein (TXNIP))

适用

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宿主

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克隆类型

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多克隆

标记

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This TXNIP antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 50-300

    纯化方法

    Protein A Chromatography

    免疫原

    A partial length recombinant TxNIP protein (amino acids 50-300) was used as the immunogen for this antibody.

    亚型

    IgG
  • 应用备注

    WB: 1-3 μg/mL

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS containing 0.05 % BSA, PH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原

    TXNIP (Thioredoxin Interacting Protein (TXNIP))

    别名

    TxNIP/VDUP1

    背景

    TXNIP (thioredoxin interacting protein) inhibits thioredoxin activity by limiting its bioavailability in response to oxidative stress. TXNIP restores COPS5-induced suppression of CDKN1B stability by interacting with COPS5 and blocks the COPS5-mediated translocation of CDKN1B from nucleus to the cytoplasm. TXNIP functions as a transcriptional repressor. TXNIP has been reported to be a suppressor of tumor cell growth and inhibits the proteasomal degradation of DDIT4, contributing to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1). TXNIP is expresed in adipose tissue, adrenal cortex, adrenal gland, amniotic fluid and amygdale.

    分子量

    44 kDa

    基因ID

    10628

    UniProt

    Q9H3M7

    途径

    Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome
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