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CRLF2 抗体 (AA 97-252)

CRLF2 适用: 人 WB 宿主: 小鼠 Monoclonal ABM28B6 unconjugated
产品编号 ABIN5027605
发货至: 中国
  • 抗原 See all CRLF2 抗体
    CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
    抗原表位
    • 15
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 97-252
    适用
    • 30
    • 26
    • 21
    宿主
    • 44
    • 8
    • 3
    小鼠
    克隆类型
    • 47
    • 8
    单克隆
    标记
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CRLF2 antibody is un-conjugated
    应用范围
    • 36
    • 26
    • 26
    • 14
    • 9
    • 6
    • 4
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB)
    纯化方法
    Protein G Chromatography
    免疫原
    A partial length recombinant TSLPR protein (amino acids 97-252) was used as the immunogen for this antibody.
    克隆位点
    ABM28B6
    亚型
    IgG2a kappa
    Top Product
    Discover our top product CRLF2 Primary Antibody
  • 应用备注
    WB: 2-4 μg/mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 0.05 % BSA, PH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原
    CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
    别名
    TSLP Receptor (CRLF2 产品)
    别名
    CRLF2 antibody, CRL2 antibody, CRLF2Y antibody, TSLPR antibody, CRLM2 antibody, Ly114 antibody, Tpte2 antibody, Tslpr antibody, Crl2 antibody, cytokine receptor like factor 2 antibody, cytokine receptor-like factor 2 antibody, CRLF2 antibody, Crlf2 antibody
    背景
    TSLPR (thymic stromal lymphopoietin receptor) also known as CRLF2 (cytokine receptor-like factor 2) is a member of type I cytokine receptor. It binds its ligand TSLP (thymic stromal lymphopoietin) as a heterodimer with IL7R. TSLP ligand is produced by epithelial cells in order to activate dendritic cells, and is involved in inflammation, allergic responses as well as B-cell precursor proliferation and survival. The interaction between TSLP and its heterodimeric receptor activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. High expression of CRLF2 is associated with a poor prognosis in adult and high-risk pediatric cases of B-ALL (B-cell acute lymphoblastic leukemias).
    分子量
    42 kDa
    基因ID
    64109
    UniProt
    Q9HC73
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