CRLF2 抗体 (AA 97-252)
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北京 101111
Quick Overview for CRLF2 抗体 (AA 97-252) (ABIN5027605)
抗原
See all CRLF2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 97-252
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纯化方法
- Protein G Chromatography
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免疫原
- A partial length recombinant TSLPR protein (amino acids 97-252) was used as the immunogen for this antibody.
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亚型
- IgG2a kappa
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anti-Cytokine Receptor-Like Factor 2 (CRLF2) (AA 81-180) antibody
CRLF2 适用: 人 ELISA, IF (p), IF (cc), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Cytokine Receptor-Like Factor 2 (CRLF2) (AA 23-231) antibodyCRLF2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cytokine Receptor-Like Factor 2 (CRLF2) (AA 23-132) antibodyCRLF2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4A11 unconjugated
anti-Cytokine Receptor-Like Factor 2 (CRLF2) (AA 23-231) antibodyCRLF2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytokine Receptor-Like Factor 2 (CRLF2) antibodyCRLF2 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 1B4 unconjugated
anti-Cytokine Receptor-Like Factor 2 (CRLF2) (AA 71-120) antibodyCRLF2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytokine Receptor-Like Factor 2 (CRLF2) antibody (Carboxyfluorescein (CFS))CRLF2 适用: 小鼠 FACS 宿主: 山羊 Polyclonal Carboxyfluorescein (CFS)
anti-Cytokine Receptor-Like Factor 2 (CRLF2) (Center) antibodyCRLF2 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Cytokine Receptor-Like Factor 2 (CRLF2) antibodyCRLF2 适用: 人 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal 8H8 unconjugated
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应用备注
- WB: 2-4 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
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别名
- TSLP Receptor
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背景
- TSLPR (thymic stromal lymphopoietin receptor) also known as CRLF2 (cytokine receptor-like factor 2) is a member of type I cytokine receptor. It binds its ligand TSLP (thymic stromal lymphopoietin) as a heterodimer with IL7R. TSLP ligand is produced by epithelial cells in order to activate dendritic cells, and is involved in inflammation, allergic responses as well as B-cell precursor proliferation and survival. The interaction between TSLP and its heterodimeric receptor activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. High expression of CRLF2 is associated with a poor prognosis in adult and high-risk pediatric cases of B-ALL (B-cell acute lymphoblastic leukemias).
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分子量
- 42 kDa
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基因ID
- 64109
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UniProt
- Q9HC73
抗原
-
