TRBP 抗体 (AA 150-366)
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Quick Overview for TRBP 抗体 (AA 150-366) (ABIN5027591)
抗原
See all TRBP (TARBP2P) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 150-366
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纯化方法
- Protein A Chromatography
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免疫原
- A partial length recombinant TRBP protein (amino acids 150-366) was used as the immunogen for this antibody.
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亚型
- IgG
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应用备注
- WB: 6-7 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- TRBP (TARBP2P) (TAR (HIV-1) RNA Binding Protein 2 Pseudogene (TARBP2P))
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别名
- TRBP
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背景
- TRBP, also known as TARBP2 (TAR (HIV-1) RNA binding protein 2) is a contributory agent of acquired immunodeficiency syndrome (AIDS). TRBP binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. It also plays a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1 and promotes translation of TAR-containing RNAs independently of EIF2AK2/PKR. Diseases associated with TARBP2 include acquired immunodeficiency syndrome. TARBP2 is highly expressed in adipose tissue, adrenal cortex, adrenal gland, amniotic fluid and amygdala. TRBP exists in two isoforms whereas alternate splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene.
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分子量
- 48 KDa
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基因ID
- 6895
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UniProt
- Q15633
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途径
- Regulatory RNA Pathways, Ribonucleoprotein Complex Subunit Organization
抗原
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