TOX3 抗体 (AA 232-442)
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北京 101111
Quick Overview for TOX3 抗体 (AA 232-442) (ABIN5027585)
抗原
See all TOX3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 232-442
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纯化方法
- Protein G Chromatography
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免疫原
- A partial length recombinant TOX-3 protein (amino acids 232-442) was used as the immunogen for this antibody
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亚型
- IgG1 kappa
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应用备注
- WB: 2-4 μg/mL, IHC: 5 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- TOX3 (TOX High Mobility Group Box Family Member 3 (TOX3))
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别名
- TOX-3
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背景
- TOX high mobility group box family member 3 (TOX-3) is a member of a subfamily of transcription factors that contains a High Mobility Group box (HMG-box), involved in bending and unwinding of DNA and alteration of chromatin structure. It has two transcript variants encoding different isoforms.TOX3 is expressed in estrogen receptor-positive mammary epithelial cells, including progenitor cells and highly expressed in luminal B breast cancers. Its over expression in human oligodendrocytes reduced cellular death under conditions mimicking Spinal cord injury (SCI).
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分子量
- 63 kDa
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基因ID
- 27324
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UniProt
- O15405
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途径
- Chromatin Binding
抗原
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