IFRD1 抗体 (AA 1-300)
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北京 101111
Quick Overview for IFRD1 抗体 (AA 1-300) (ABIN5027565)
抗原
See all IFRD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-300
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纯化方法
- Protein A Chromatography
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免疫原
- A partial length recombinant Tis7 protein (amino acids 1-300) was used as the immunogen for this antibody.
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亚型
- IgG
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应用备注
- WB: 2-4 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- IFRD1 (Interferon Related Developmental Regulator 1 (IFRD1))
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别名
- Tis7
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背景
- Tis7/IFRD1 (interferon-related developmental regulator 1) is expressed by neutrophils as a key modifier gene in cystic fibrosis (CF) lung disease. It functions as a transcriptional co-activator/repressor that controls the growth and differentiation of specific cell types during embryonic development and tissue regeneration. In skeletal muscle cells, Tis7 is known to function as a coactivator of MyoD by promoting the transcriptional activity of myocyte enhancer factor 2C (MEF2C). Mutations in Tis7 are associated with sensory/motor neuropathy with ataxia.
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分子量
- 55 kDa
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基因ID
- 3475
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UniProt
- O00458
抗原
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