SWAP70 抗体 (AA 300-505)
Our Local Distributor
北京 101111
Quick Overview for SWAP70 抗体 (AA 300-505) (ABIN5027555)
抗原
See all SWAP70 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 300-505
-
纯化方法
- Protein A Chromatography
-
免疫原
- A partial length recombinant SWAP70 protein (amino acids 300-505) was used as the immunogen for this antibody.
-
亚型
- IgG
-
-
anti-SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70) (AA 378-451) antibody
SWAP70 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H8 unconjugated
anti-SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70) (AA 378-451) antibodySWAP70 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3H8 unconjugated
anti-SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70) (AA 316-585) antibodySWAP70 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70) (C-Term) antibodyVerified SWAP70 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70) (AA 1-585) antibodySWAP70 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70) (AA 1-585) antibodySWAP70 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70) antibodySWAP70 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70) antibodySWAP70 适用: 人, 小鼠 WB, IP 宿主: 小鼠 Monoclonal unconjugated
anti-SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70) (AA 1-50) antibodySWAP70 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70) antibodyKD Validated SWAP70 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 25GB4225 unconjugated
-
-
应用备注
- WB: 2-4 μg/mL
-
限制
- 仅限研究用
-
-
-
浓度
- 0.5 mg/mL
-
缓冲液
- PBS containing 0.05 % BSA, PH 7.4
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
-
-
- SWAP70 (SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70))
-
别名
- SWAP70
-
背景
- SWAP-70 is a 70 kDa multiple functional signaling proteins involved in formation of membrane ruffling induced by signal cascade of tyrosine kinase growth factor receptors. It is involved in regulating migration and invasion of trophoblast cells during the processes of embryonic implantation and placentation in primates. Though originally isolated from activated B lymphocytes, recently it has been found that it is widely expressed in various cell types and tissues. It has a high binding afinity to PI(3,4)P2. Its intracellular localization has been reported to depend on cell activation. Stimulation of the B cell receptor triggers a translocation of SWAP-70 from the cytosol to the plasma membrane in B cells. This translocation required a functional PH-domain. SWAP-70 functions as the only B cell-specific component of an isotype switch recombination complex called SWAP. The SWAP complex has specificity for the switch regions upstream of the constant region immunoglobulin genes and it facilitates the transfer of DNA between switch regions. These features suggested that mutations in the gene encoding SWAP-70 might result in humoral immunodeficiency.
-
分子量
- 64 kDa
-
基因ID
- 23075
-
UniProt
- Q9UH65
-
途径
- Production of Molecular Mediator of Immune Response
抗原
-
