SPIB 抗体 (AA 50-260)
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Quick Overview for SPIB 抗体 (AA 50-260) (ABIN5027543)
抗原
See all SPIB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 50-260
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纯化方法
- Protein A Chromatography
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免疫原
- A partial length recombinant Spi-B protein (amino acids 50-260) was used as the immunogen for this antibody.
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亚型
- IgG
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应用备注
- WB: 2-4 μg/mL, IHC: 5 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- SPIB (Spi-B Transcription Factor (Spi-1/PU.1 Related) (SPIB))
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别名
- Spi-B
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背景
- Spi-B belongs to the ETS family transcription containing a conserved ETS domain which specifically binds to a purine-rich DNA sequence called the PU-box (5'-GAGGAA-3'). Spi-B has two known isoforms (28 and 18 kDa) localized in nucleus and cytoplasm. Spi-B contains two transactivation domains (TAD) at the N- terminal end which may be required for transcriptional activation of the target genes. Spi-B is involved in development of plasmacytoid dendritic cells (natural interferon producing cells) and B-cell development. Spi-B acts as a lymphoid specific enhancer. Spi-B is highly expressed in plasmacytoid dendritic cells (pDCs), B-cells and stem cell populations of the liver.
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分子量
- 28 kDa
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基因ID
- 6689
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UniProt
- Q01892
抗原
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