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RAX 抗体 (AA 100-313)

RAX 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5027505
发货至: 中国
  • 抗原 See all RAX 抗体
    RAX (Retina and Anterior Neural Fold Homeobox (RAX))
    抗原表位
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    AA 100-313
    适用
    • 17
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 12
    • 5
    克隆类型
    • 12
    • 5
    多克隆
    标记
    • 15
    • 1
    • 1
    This RAX antibody is un-conjugated
    应用范围
    • 15
    • 8
    • 3
    • 2
    • 1
    Western Blotting (WB)
    纯化方法
    Protein A Chromatography
    免疫原
    A partial length recombinant RAX protein (amino acids 100-313) was used as the immunogen for this antibody.
    亚型
    IgG
    Top Product
    Discover our top product RAX Primary Antibody
  • 应用备注
    WB: 1-2 μg/mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 0.05 % BSA, PH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原
    RAX (Retina and Anterior Neural Fold Homeobox (RAX))
    别名
    RAX (RAX 产品)
    别名
    MCOP3 antibody, RX antibody, 7530406A22Rik antibody, E130303K03Rik antibody, Rx antibody, ey-1 antibody, ey1 antibody, RAX antibody, rx antibody, rx1 antibody, Rx2A antibody, Xrax antibody, Xrx1 antibody, rax antibody, CG10052 antibody, DRx antibody, Dmel\\CG10052 antibody, Drx antibody, E97 antibody, PPH17 antibody, W60 antibody, bk50 antibody, drx antibody, wom antibody, Xrx2 antibody, rax-a antibody, rax1 antibody, rx1a antibody, rx2a antibody, retina and anterior neural fold homeobox antibody, Retinal Homeobox antibody, retina and anterior neural fold homeobox L homeolog antibody, retina and anterior neural fold homeobox S homeolog antibody, RAX antibody, Rax antibody, rax antibody, Rx antibody, rax.L antibody, rax.S antibody
    背景
    RAX or PRKRA (retina and anterior neural fold homeobox) is a homeobox-containing transcription factor. It plays an important role in eye development by regulating the initial specification of retinal cells. In the absence of double-stranded RNA, RAX activates EIF2AK2/PKR, so as to phosphorylate EIF2S1/EFI2-alpha leading to inhibition of translation and induction of apoptosis. RAX has been reported to be essential for siRNA production by DICER1 and for subsequent siRNA-mediated post-transcriptional gene silencing. Mutations in this gene have been reported in patients with defects in ocular development, including microphthalmia, anophthalmia and coloboma. RAX is expressed in blood, bone, brain, spleen and adipose tissues.
    分子量
    30 kDa
    基因ID
    8575
    UniProt
    O75569
    途径
    Regulatory RNA Pathways
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