RAX 抗体 (AA 100-313)
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北京 101111
Quick Overview for RAX 抗体 (AA 100-313) (ABIN5027505)
抗原
See all RAX 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 100-313
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纯化方法
- Protein A Chromatography
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免疫原
- A partial length recombinant RAX protein (amino acids 100-313) was used as the immunogen for this antibody.
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亚型
- IgG
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应用备注
- WB: 1-2 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- RAX (Retina and Anterior Neural Fold Homeobox (RAX))
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别名
- RAX
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背景
- RAX or PRKRA (retina and anterior neural fold homeobox) is a homeobox-containing transcription factor. It plays an important role in eye development by regulating the initial specification of retinal cells. In the absence of double-stranded RNA, RAX activates EIF2AK2/PKR, so as to phosphorylate EIF2S1/EFI2-alpha leading to inhibition of translation and induction of apoptosis. RAX has been reported to be essential for siRNA production by DICER1 and for subsequent siRNA-mediated post-transcriptional gene silencing. Mutations in this gene have been reported in patients with defects in ocular development, including microphthalmia, anophthalmia and coloboma. RAX is expressed in blood, bone, brain, spleen and adipose tissues.
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分子量
- 30 kDa
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基因ID
- 8575
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UniProt
- O75569
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途径
- Regulatory RNA Pathways
抗原
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