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RAX 抗体 (AA 100-313)

This anti-RAX antibody is a 兔 多克隆 antibody detecting RAX in WB. Suitable for 人.
产品编号 ABIN5027505
发货至: 中国

Quick Overview for RAX 抗体 (AA 100-313) (ABIN5027505)

抗原

See all RAX 抗体
RAX (Retina and Anterior Neural Fold Homeobox (RAX))

适用

  • 17
  • 7
  • 7
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1

宿主

  • 12
  • 5

克隆类型

  • 12
  • 5
多克隆

标记

  • 15
  • 1
  • 1
This RAX antibody is un-conjugated

应用范围

  • 15
  • 8
  • 3
  • 2
  • 2
Western Blotting (WB)
  • 抗原表位

    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 100-313

    纯化方法

    Protein A Chromatography

    免疫原

    A partial length recombinant RAX protein (amino acids 100-313) was used as the immunogen for this antibody.

    亚型

    IgG
  • 应用备注

    WB: 1-2 μg/mL

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS containing 0.05 % BSA, PH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原

    RAX (Retina and Anterior Neural Fold Homeobox (RAX))

    别名

    RAX

    背景

    RAX or PRKRA (retina and anterior neural fold homeobox) is a homeobox-containing transcription factor. It plays an important role in eye development by regulating the initial specification of retinal cells. In the absence of double-stranded RNA, RAX activates EIF2AK2/PKR, so as to phosphorylate EIF2S1/EFI2-alpha leading to inhibition of translation and induction of apoptosis. RAX has been reported to be essential for siRNA production by DICER1 and for subsequent siRNA-mediated post-transcriptional gene silencing. Mutations in this gene have been reported in patients with defects in ocular development, including microphthalmia, anophthalmia and coloboma. RAX is expressed in blood, bone, brain, spleen and adipose tissues.

    分子量

    30 kDa

    基因ID

    8575

    UniProt

    O75569

    途径

    Regulatory RNA Pathways
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