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IL3RA 抗体 (AA 120-323)

IL3RA 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal ABM25C1 unconjugated
产品编号 ABIN5027448
发货至: 中国
  • 抗原 See all IL3RA 抗体
    IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
    抗原表位
    • 16
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 120-323
    适用
    • 77
    • 26
    • 3
    宿主
    • 48
    • 32
    • 3
    • 1
    小鼠
    克隆类型
    • 45
    • 38
    • 1
    单克隆
    标记
    • 42
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL3RA antibody is un-conjugated
    应用范围
    • 58
    • 47
    • 17
    • 15
    • 13
    • 13
    • 10
    • 8
    • 8
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    纯化方法
    Protein G Chromatography
    免疫原
    A partial length recombinant protein (a.a 120-323) of IL-3RA was used as the immunogen for this antibody.
    克隆位点
    ABM25C1
    亚型
    IgG2b kappa
    Top Product
    Discover our top product IL3RA Primary Antibody
  • 应用备注
    WB: 6-8 μg/mL, FACS: 0.5-1 μg/10^6
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 0.05 % BSA, PH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原
    IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
    别名
    IL-3RA (IL3RA 产品)
    别名
    CD123 antibody, IL3R antibody, IL3RAY antibody, IL3RX antibody, IL3RY antibody, hIL-3Ra antibody, CDw123 antibody, SUT-1 antibody, Cyrl antibody, interleukin 3 receptor subunit alpha antibody, interleukin 3 receptor, alpha chain antibody, IL3RA antibody, Il3ra antibody
    背景
    Interleukin-3 receptor subunit alpha (IL-3RA) or CD123 is a high-affinity receptor for interleukin-3 (IL-3), which along with the primary signaling common Beta (Beta c) subunit (CD131) forms a heterodimer, enabling cell signaling. IL-3RA chain is a glycoprotein of 360 amino acidic residues, composed by an extracellular domain of 287 amino acid residues, involving a predicted Ig-like domain, two Fn III domains, a transmembrane domain of 30 amino acid residues and by an intracellular domain of 53 residues. It is expressed on the majority of CD34+ hemopoietic progenitors and its expression is rapidly lost during erythroid and megakaryocytic differentiation, moderately decreased during monocytic differentiation and is sustained in the granulocytic lineage. IL-3RA is also expressed in a variety of hematological neoplasms including blastic plasmacytoid dendritic cell neoplasm (BPDCN), acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), chronic myeloid leukemia (CML), Hodgkin&rsquo,s lymphoma and hairy cell leukemia.
    分子量
    44 kDa
    基因ID
    3563
    UniProt
    P26951
    途径
    JAK/STAT Signaling
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