POU3F2 抗体 (AA 220-421)
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北京 101111
Quick Overview for POU3F2 抗体 (AA 220-421) (ABIN5027442)
抗原
See all POU3F2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 220-421
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纯化方法
- Protein A Chromatography
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免疫原
- A partial length recombinant POU3F2 protein (amino acids 220-421) was used as the immunogen for this antibody.
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亚型
- IgG
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应用备注
- WB: 1-2 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- POU3F2 (POU Class 3 Homeobox 2 (POU3F2))
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别名
- POU3F2
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背景
- POU3F2 is a developmental neural cell-specific POU domain transcription factor and is crucial for cell lineage determination. In melanoma lesions, cells expressing high levels of POU3F2 show enhanced invasive and metastatic capacity that can in part be explained by repression of MITF (Micropthalmia-associated Transcription Factor) expression via POU3F2 binding to its promoter. POU3F2 is expressed exclusively in the central nervous system, more specifically in postmitotic neurons and glia.
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分子量
- 27 kDa
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基因ID
- 5454
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UniProt
- P20265
抗原
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