PTH 抗体 (AA 1-236)
Quick Overview for PTH 抗体 (AA 1-236) (ABIN5027426)
抗原
See all PTH 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-236
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纯化方法
- Protein G Chromatography
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免疫原
- A partial length recombinant Parathyroid Hormone protein (amino acids 1-236) was used as the immunogen for this antibody
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亚型
- IgG2b kappa
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anti-Parathyroid Hormone (PTH) antibody
PTH 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Parathyroid Hormone (PTH) (AA 32-115) antibodyPTH 适用: 人 IHC, StM 宿主: 兔 Monoclonal PTH-2295R unconjugated Recombinant Antibody
anti-Parathyroid Hormone (PTH) (AA 1-34) antibodyPTH 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-525R unconjugated Recombinant Antibody
anti-Parathyroid Hormone (PTH) (AA 32-115) antibodyPTH 适用: 大鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Parathyroid Hormone (PTH) (AA 32-115) antibodyPTH 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Parathyroid Hormone (PTH) (AA 32-115) antibodyPTH 适用: 人 IHC, WB, IHC (p) 宿主: 小鼠 Monoclonal 1C6 unconjugated
anti-Parathyroid Hormone (PTH) antibodyPTH 适用: 人 IHC, IHC (p), HIER 宿主: 小鼠 Monoclonal 105G7 unconjugated
anti-Parathyroid Hormone (PTH) (AA 1-34) antibodyPTH 适用: 人 IHC, StM 宿主: 兔 Monoclonal PTH-1717R unconjugated Recombinant Antibody
anti-Parathyroid Hormone (PTH) (AA 1-34) antibodyPTH 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal rPTH-911 unconjugated Recombinant Antibody
anti-Parathyroid Hormone (PTH) (AA 71-115) antibodyPTH 适用: 人 IHC, ELISA, IHC (p) 宿主: 山羊 Polyclonal unconjugated
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应用备注
- WB: 2-4 μg/mL, IHC: 5 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- PTH (Parathyroid Hormone (PTH))
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别名
- Parathyroid Hormone
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物质类
- Hormone
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背景
- Parathyroid hormone (PTH) produced and secreted by parathyroid glands, maintains mineral homeostasis by regulating calcium and phosphate absorption/reabsorption. It modulates phosphate homeostasis by downregulating Dentin matrix acidic phosphoprotein 1(DMP1) expression via the cAMP/PKA pathway targeting genes/proteins mutually governed by PTH. PTH secretion is characterized by an ultradian rhythm with tonic and pulsatile components. The majority of PTH is secreted in tonic fashion. Changes in the ultradian PTH secretion are correlated with skeletal fragility in primary and secondary osteoporosis. Plasma concentrations of Zn ions levels were significantly correlated with PTH levels. PTH in serum is typical for patients with chronic kidney disease (CKD). The onset of CKD is associated with pathway changes of protein synthesis and metabolism, amino acid metabolism, energy metabolism, and steroid hormone metabolism. Parathyroid hormones are bone-forming agents that have different modes of action on the bone. Lack of PTH in the central nervous system causes Hypoparathyroidism (HPT).
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分子量
- 59 kDa
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基因ID
- 5745
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UniProt
- Q03431
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途径
- cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process
抗原
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