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MUL1 抗体 (AA 146-352)

MUL1 适用: 人 WB 宿主: 小鼠 Monoclonal ABM4F71 unconjugated
产品编号 ABIN5027374
发货至: 中国
  • 抗原 See all MUL1 抗体
    MUL1 (Mitochondrial E3 Ubiquitin Protein Ligase 1 (MUL1))
    抗原表位
    • 18
    • 9
    • 8
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 146-352
    适用
    • 46
    • 24
    • 21
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    宿主
    • 45
    • 1
    小鼠
    克隆类型
    • 46
    单克隆
    标记
    • 19
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MUL1 antibody is un-conjugated
    应用范围
    • 44
    • 16
    • 15
    • 14
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Protein G Chromatography
    免疫原
    A partial length recombinant MUL1 protein (amino acids 146-352) was used as the immunogen for this antibody.
    克隆位点
    ABM4F71
    亚型
    IgG1
    Top Product
    Discover our top product MUL1 Primary Antibody
  • 应用备注
    WB: 4-8 μg/mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 0.05 % BSA, PH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原
    MUL1 (Mitochondrial E3 Ubiquitin Protein Ligase 1 (MUL1))
    别名
    MUL1 (MUL1 产品)
    别名
    C1orf166 antibody, GIDE antibody, MAPL antibody, MULAN antibody, RNF218 antibody, RP11-401M16.2 antibody, mul1 antibody, zgc:92166 antibody, 0610009K11Rik antibody, AV000801 antibody, Gide antibody, RGD1309944 antibody, im:7146383 antibody, zgc:165594 antibody, mitochondrial E3 ubiquitin protein ligase 1 antibody, mitochondrial E3 ubiquitin protein ligase 1 L homeolog antibody, mitochondrial E3 ubiquitin protein ligase 1a antibody, mitochondrial ubiquitin ligase activator of NFKB 1 antibody, mitochondrial E3 ubiquitin protein ligase 1b antibody, MUL1 antibody, mul1.L antibody, mul1a antibody, Mul1 antibody, mul1b antibody
    背景
    MUL1 (Mitochondrial E3 Ubiquitin Protein Ligase-1) is a crucial moderator of RIG-I (Retinoic Acid-Inducible-Gene-I) signaling. This protein is localized to the mitochondria where it interacts with MAVS (Mitochondrial Antiviral Signaling) and catalyzes RIG-I post-translational modifications that inhibit RIG-I-dependent cell signaling. MUL1 contains a unique BAM (Beside A Membrane) domain and a C-terminal RING-finger domain. This protein has been implicated in several processes that occur in animal cells such as NF-KappaB activation, innate immunity and antiviral signaling, suppression of PINK1/parkin defects, mitophagy in skeletal muscle, and caspase-dependent apoptosis.
    分子量
    40 kDa
    基因ID
    79594
    UniProt
    Q969V5
    途径
    Positive Regulation of Endopeptidase Activity
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