MUL1 抗体 (AA 146-352)
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Quick Overview for MUL1 抗体 (AA 146-352) (ABIN5027374)
抗原
See all MUL1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 146-352
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纯化方法
- Protein G Chromatography
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免疫原
- A partial length recombinant MUL1 protein (amino acids 146-352) was used as the immunogen for this antibody.
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亚型
- IgG1
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应用备注
- WB: 4-8 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- MUL1 (Mitochondrial E3 Ubiquitin Protein Ligase 1 (MUL1))
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别名
- MUL1
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背景
- MUL1 (Mitochondrial E3 Ubiquitin Protein Ligase-1) is a crucial moderator of RIG-I (Retinoic Acid-Inducible-Gene-I) signaling. This protein is localized to the mitochondria where it interacts with MAVS (Mitochondrial Antiviral Signaling) and catalyzes RIG-I post-translational modifications that inhibit RIG-I-dependent cell signaling. MUL1 contains a unique BAM (Beside A Membrane) domain and a C-terminal RING-finger domain. This protein has been implicated in several processes that occur in animal cells such as NF-KappaB activation, innate immunity and antiviral signaling, suppression of PINK1/parkin defects, mitophagy in skeletal muscle, and caspase-dependent apoptosis.
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分子量
- 40 kDa
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基因ID
- 79594
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UniProt
- Q969V5
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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