MAPKAP1 抗体 (AA 250-522)
Our Local Distributor
北京 101111
Quick Overview for MAPKAP1 抗体 (AA 250-522) (ABIN5027356)
抗原
See all MAPKAP1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 250-522
-
纯化方法
- Protein A Chromatography
-
免疫原
- A partial length recombinant Mip1 protein (amino acids 250-522) was used as the immunogen for this antibody.
-
亚型
- IgG
-
-
-
-
应用备注
- WB: 1-3 μg/mL
-
限制
- 仅限研究用
-
-
-
浓度
- 0.5 mg/mL
-
缓冲液
- PBS containing 0.05 % BSA, PH 7.4
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
-
-
- MAPKAP1 (Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1))
-
别名
- SAPK interacting proten 1/Mip1
-
背景
- Stress-activated map kinase (SAPK )-interacting protein 1, also called as Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1), belongs to Stress-activated map kinase interacting protein 1 (SIN1) family. It is a subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors and also plays a critical role in AKT1 'Ser-473'phosphorylation. Except isoform 4 from its 6 isoforms , all can be incorporated into the mammalian target of rapamycin complex 2 (mTORC2) which contains MTOR, MLST8, PRR5, RICTOR, MAPKAP1 and DEPTOR. It is ubiquitously expressed in heart and skeletal muscle. Diseases associated with MAPKAP1 include bronchiolitis obliterans organizing pneumonia and nephrogenic systemic fibrosis.
-
分子量
- 50 kDa
-
基因ID
- 79109
-
UniProt
- Q9BPZ7
-
途径
- PI3K-Akt Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events
抗原
-