MEIS1 抗体 (AA 163-352)
Quick Overview for MEIS1 抗体 (AA 163-352) (ABIN5027352)
抗原
See all MEIS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 163-352
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纯化方法
- Protein A Chromatography
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免疫原
- A partial length recombinant MEIS1 protein (amino acids 163-352) was used as the immunogen for this antibody.
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亚型
- IgG
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应用备注
- WB: 1-2 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- MEIS1 (Meis Homeobox 1 (MEIS1))
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别名
- MEIS1
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背景
- Myeloid ecotropoic viral insertion site 1 (MEIS1) is a transcription factor belonging to TALE (three amino acids loop extension) family. The gene for MEIS1 is mapped to human chromosome 2p15. The amino terminus contains binding domains for its interaction partners, the transcription factors HOXA9 and PBX1, followed by a homeobox DNA binding domain and carboxy-terminal transcriptional activation domains. It is expressed in hematopoietic stem and progenitor cells and increases during human megakaryocytic differentiation. MEIS1 plays a role in the normal development of the hematopoietic lineage and is over expressed in a subset of acute myeloid leukemias. Increased MEIS1 expression has also been observed in neuroblastomas and the expression level of the MEIS1 transcript is a prognostic indicator in breast cancer.
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分子量
- 43 kDa
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基因ID
- 4211
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UniProt
- O00470
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途径
- Chromatin Binding
抗原
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