MBD3 抗体 (AA 1-290)
Quick Overview for MBD3 抗体 (AA 1-290) (ABIN5027348)
抗原
See all MBD3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-290
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纯化方法
- Protein G Chromatography
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免疫原
- A partial length recombinant MBD3 protein (amino acids 1-290) was used as the immunogen for this antibody.
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亚型
- IgG1 kappa
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anti-Methyl-CpG Binding Domain Protein 3 (MBD3) (AA 79-209) antibody
MBD3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 3 (MBD3) (AA 70-179) antibodyMBD3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 3 (MBD3) (AA 1-291) antibodyMBD3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 3 (MBD3) (C-Term) antibodyMBD3 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 3 (MBD3) (AA 1-255) antibodyMBD3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 3 (MBD3) antibodyMBD3 适用: 人 WB 宿主: 小鼠 Monoclonal 5C3 unconjugated
anti-Methyl-CpG Binding Domain Protein 3 (MBD3) (C-Term) antibodyMBD3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 3 (MBD3) (AA 72-121) antibodyMBD3 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 猴, Cow, 马, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 3 (MBD3) (C-Term) antibodyMBD3 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 3 (MBD3) (AA 265-291) antibodyMBD3 适用: 人 IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 2-4 μg/mL, IHC: 5 μg/mL, FACS: 0.5 μg/10^6 cells
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))
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别名
- MBD2/MBD3
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背景
- MBD2 is a subunit of the NuRD complex that is postulated to mediate gene repression via recruitment of the complex to methylated DNA. This protein binds around 1 kb downstream of the transcription start site of a subset of 400 CpG island promoters that are characterized by the presence of active histone marks, RNA polymerase II (Pol2) and low to medium gene expression levels and H3K36me3 deposition. Methylated MBD2 is involved in silencing methylated tumor suppressor genes as well as activation of pro-metastatic genes. MBD2 also plays a key role in regulating expression of a range of genes that are associated with optimal DC (Dendritic cells) activation and function.
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分子量
- 32. 44 kDa
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基因ID
- 53615
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UniProt
- O95983
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途径
- Chromatin Binding
抗原
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