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MAFA 抗体 (AA 192-353)

This 兔 多克隆 anti-MAFA antibody specifically detects MAFA in WB. The antibody is reactive with 人 samples.
产品编号 ABIN5027344
发货至: 中国
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Quick Overview for MAFA 抗体 (AA 192-353) (ABIN5027344)

抗原

See all MAFA 抗体
MAFA (Transcription Factor MafA (MAFA))

适用

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宿主

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克隆类型

  • 49
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多克隆

标记

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This MAFA antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 192-353

    纯化方法

    Protein A Chromatography

    免疫原

    A partial length recombinant Mafa protein (amino acids 192-353) was used as the immunogen for this antibody.

    亚型

    IgG
  • 应用备注

    WB: 1-2 μg/mL

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS containing 0.05 % BSA, PH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原

    MAFA (Transcription Factor MafA (MAFA))

    别名

    Mafa

    背景

    Musculoaponeurotic fibrosarcoma oncogene family A (MafA) is a pancreatic transcriptional factor that is important to pancreatic beta-cell function. It is a member of the musculo-aponeurotic fibrosarcoma oncogene family, a subgroup of the basic leucine zipper transcription factors with homology to the v-Maf oncoprotein. It acts as a transcriptional regulator that promotes the expression of genes important in glucose-induced insulin secretion, such as insulin, glucokinase and glucose transporter protein-2. Mafa is unique in being exclusively expressed at the secondary and principal phase of insulin-expressing cell production during pancreas organogenesis and is the only transcriptional activator present exclusively in islet beta-cells thus may be involved in pathogenesis of diabetes.

    分子量

    36 kDa

    基因ID

    389692

    UniProt

    Q8NHW3

    途径

    Hormone Transport
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