MAFA 抗体 (AA 192-353)
Our Local Distributor
北京 101111
Quick Overview for MAFA 抗体 (AA 192-353) (ABIN5027344)
抗原
See all MAFA 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 192-353
-
纯化方法
- Protein A Chromatography
-
免疫原
- A partial length recombinant Mafa protein (amino acids 192-353) was used as the immunogen for this antibody.
-
亚型
- IgG
-
-
-
-
应用备注
- WB: 1-2 μg/mL
-
限制
- 仅限研究用
-
-
-
浓度
- 0.5 mg/mL
-
缓冲液
- PBS containing 0.05 % BSA, PH 7.4
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
-
-
- MAFA (Transcription Factor MafA (MAFA))
-
别名
- Mafa
-
背景
- Musculoaponeurotic fibrosarcoma oncogene family A (MafA) is a pancreatic transcriptional factor that is important to pancreatic beta-cell function. It is a member of the musculo-aponeurotic fibrosarcoma oncogene family, a subgroup of the basic leucine zipper transcription factors with homology to the v-Maf oncoprotein. It acts as a transcriptional regulator that promotes the expression of genes important in glucose-induced insulin secretion, such as insulin, glucokinase and glucose transporter protein-2. Mafa is unique in being exclusively expressed at the secondary and principal phase of insulin-expressing cell production during pancreas organogenesis and is the only transcriptional activator present exclusively in islet beta-cells thus may be involved in pathogenesis of diabetes.
-
分子量
- 36 kDa
-
基因ID
- 389692
-
UniProt
- Q8NHW3
-
途径
- Hormone Transport
抗原
-