KLF4 抗体 (AA 1-300)
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北京 101111
Quick Overview for KLF4 抗体 (AA 1-300) (ABIN5027332)
抗原
See all KLF4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-300
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纯化方法
- Protein A Chromatography
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免疫原
- A partial length recombinant KLF4 protein (amino acids 1-300) was used as the immunogen for this antibody.
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亚型
- IgG
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应用备注
- WB: 2-4 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))
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别名
- KLF4/GKLF
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背景
- Kruppel like factor 4 (KLF4) which are also called as gun enriched kruppel like factors (GKLF) is a member of SP/KLF family of zinc transcription factors that are involved in numerous important cellular processes, such as, proliferation, inflammation, apoptosis and somatic cell reprogramming. The Kruppel zinc finger transcription factor was initially identified in Drosophila as a segmented gene. This protein is found to inhibit cell proliferation by functioning as a cell cycle checkpoint protein that leads to activation of transcription of the cyclin-dependent kinase inhibitor. Clinically KLF4 plays a role in the pathogenesis of esophageal cancer and malaria. It has five isoform that are produced by alternate splicing. Expression of KLF4 is highly enriched in the post replicative epithelial cells of the intestine, skin and thymus.
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分子量
- 55 kDa
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基因ID
- 9314
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UniProt
- O43474
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途径
- Peptide Hormone Metabolism, Stem Cell Maintenance
抗原
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