KLF10/TIEG1 抗体 (AA 11-221)
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Quick Overview for KLF10/TIEG1 抗体 (AA 11-221) (ABIN5027328)
抗原
See all KLF10/TIEG1 (KLF10) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 11-221
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纯化方法
- Protein A Chromatography
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免疫原
- A partial length recombinant KLF10 protein (amino acids 11-221) was used as the immunogen for this antibody.
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亚型
- IgG
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应用备注
- WB: 1-2 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- KLF10/TIEG1 (KLF10) (Kruppel-Like Factor 10 (KLF10))
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别名
- KLF10
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背景
- Kruppel-like factor 10 (KLF10 ) is a member of the Kruppel-like family of transcription factors, which are known to be involved in anti-proliferative and apoptotic inducing functions following TGF-beta induction. KLF10 plays an important role in the repression of proliferative and hypertrophic pathways, possibly through the actions of PTTG1 (pituitary tumor-transforming gene 1). KLF10 is found to be predominantly expressed in various tissues and its expression is regulated by cytokines and growth factors. Over-expression of KLF10 has been found to induce apoptosis in pancreatic cancer cells. In addition, KLF10 induces apoptosis via a mechanism which involves the formation of reactive oxygen species.
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分子量
- 46 kDa
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基因ID
- 7071
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UniProt
- Q13118
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途径
- Stem Cell Maintenance
抗原
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