JMJD5 抗体 (AA 20-220)
Our Local Distributor
北京 101111
Quick Overview for JMJD5 抗体 (AA 20-220) (ABIN5027324)
抗原
See all JMJD5 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 20-220
-
纯化方法
- Protein A Chromatography
-
免疫原
- A partial length recombinant JMJD5 protein (amino acids 20-220) was used as the immunogen for this antibody.
-
亚型
- IgG
-
-
-
-
应用备注
- WB: 2-4 μg/mL
-
限制
- 仅限研究用
-
-
-
浓度
- 0.5 mg/mL
-
缓冲液
- PBS containing 0.05 % BSA, PH 7.4
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
-
-
- JMJD5 (Jumonji Domain Containing 5 (JMJD5))
-
别名
- JMJD5
-
背景
- JMJD5 (Jumonji domain-containing protein 5) or commonly called as Lysine-specific demethylase 8 is a histone lysine demethylase that specifically demethylates dimethylated Lys 36 of histone H3 (H3K36me2) thereby activating the target gene. JMJD5 is important for G2/M phase cell cycle progression. JMJD5 is also a potential tumor suppression protein. JMJD5 helps in regulation of cancer proliferation by regulating cyclin-A1. JMJD5 has three isoforms (47, 24, 50 kDa), all localized in nucleus. JMJD5 is weakly expressed in most normal cells but highly expressed in breast cancer cells.
-
分子量
- 47 kDa
-
基因ID
- 79831
-
UniProt
- Q8N371
-
途径
- Chromatin Binding
抗原
-