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JMJD5 抗体 (AA 20-220)

This anti-JMJD5 antibody is a 兔 多克隆 antibody detecting JMJD5 in WB. Suitable for 人.
产品编号 ABIN5027324
发货至: 中国

Quick Overview for JMJD5 抗体 (AA 20-220) (ABIN5027324)

抗原

See all JMJD5 抗体
JMJD5 (Jumonji Domain Containing 5 (JMJD5))

适用

  • 36
  • 8
  • 7
  • 6
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1

宿主

  • 33
  • 3

克隆类型

  • 34
  • 2
多克隆

标记

  • 21
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This JMJD5 antibody is un-conjugated

应用范围

  • 23
  • 16
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 10
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 20-220

    纯化方法

    Protein A Chromatography

    免疫原

    A partial length recombinant JMJD5 protein (amino acids 20-220) was used as the immunogen for this antibody.

    亚型

    IgG
  • 应用备注

    WB: 2-4 μg/mL

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS containing 0.05 % BSA, PH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原

    JMJD5 (Jumonji Domain Containing 5 (JMJD5))

    别名

    JMJD5

    背景

    JMJD5 (Jumonji domain-containing protein 5) or commonly called as Lysine-specific demethylase 8 is a histone lysine demethylase that specifically demethylates dimethylated Lys 36 of histone H3 (H3K36me2) thereby activating the target gene. JMJD5 is important for G2/M phase cell cycle progression. JMJD5 is also a potential tumor suppression protein. JMJD5 helps in regulation of cancer proliferation by regulating cyclin-A1. JMJD5 has three isoforms (47, 24, 50 kDa), all localized in nucleus. JMJD5 is weakly expressed in most normal cells but highly expressed in breast cancer cells.

    分子量

    47 kDa

    基因ID

    79831

    UniProt

    Q8N371

    途径

    Chromatin Binding
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