Importin 8 抗体 (AA 700-1000)
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北京 101111
Quick Overview for Importin 8 抗体 (AA 700-1000) (ABIN5027312)
抗原
See all Importin 8 (IPO8) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 700-1000
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纯化方法
- Protein A Chromatography
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免疫原
- A partial length recombinant Importin-8 protein (amino acids 700-1,000) was used as the immunogen for this antibody.
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亚型
- IgG
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anti-Importin 8 (IPO8) (AA 878-1037) antibody
IPO8 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Importin 8 (IPO8) (AA 417-622) antibodyIPO8 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Importin 8 (IPO8) antibodyIPO8 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Importin 8 (IPO8) (AA 949-1037) antibodyIPO8 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 3D5 unconjugated
anti-Importin 8 (IPO8) (AA 850-900) antibodyIPO8 适用: 人, 猴 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Importin 8 (IPO8) antibodyIPO8 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Importin 8 (IPO8) (C-Term) antibodyVerified IPO8 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
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应用备注
- WB: 2-4 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- Importin 8 (IPO8)
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别名
- Importin-8
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背景
- Importin-8 is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. It acts as a nuclear protein involved in the nucleolar transport. Importin-8 is required for cytoplasmic miRNA-guided gene silencing and is involved in loading Ago complexes into a variety of different mRNA targets, affecting the nuclear localization of Ago proteins. This protein binds to the nuclear pore complex and, along with RanGTP and RANBP1, inhibits the GAP stimulation of the Ran GTPase. The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. Importin-8 has been proposed previously as a reference gene in the human motor cortex as it showed no differences in a study with different brain regions from chronic alcoholics and control subjects and lung samples.
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分子量
- 118 kDa
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基因ID
- 10526
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UniProt
- O15397
抗原
-
