IPO7 抗体 (AA 1-322)
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北京 101111
Quick Overview for IPO7 抗体 (AA 1-322) (ABIN5027310)
抗原
See all IPO7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-322
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纯化方法
- Protein A Chromatography
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免疫原
- A partial length recombinant Importin 7 protein (amino acids 1-322) was used as the immunogen for this antibody.
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亚型
- IgG
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应用备注
- WB: 1-2 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- IPO7 (Importin 7 (IPO7))
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别名
- Importin 7
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背景
- Importin 7 (IPO7) is a soluble nuclear transport factor that is required for efficient import. It mediates transport of hTERT into the nucleus. Efficient transport also requires the cytoplasmic nucleoporin Nup358, which was previously implicated in nuclear import of a subset of proteins. Importin 7 plays an important role in nuclear protein import either by acting as autonomous nuclear transport receptor, or as an adapter like protein in association with the importin-beta subunit KPNB1. It serves itself as receptor for nuclear localization signals (NLS) and to promote translocation of import substrates through the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism.
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分子量
- 115 kDa
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基因ID
- 10527
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UniProt
- O95373
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途径
- Protein targeting to Nucleus
抗原
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