IL1RL2 抗体 (AA 1-203)
Our Local Distributor
北京 101111
Quick Overview for IL1RL2 抗体 (AA 1-203) (ABIN5027302)
抗原
See all IL1RL2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 1-203
-
纯化方法
- Protein G Chromatography
-
免疫原
- A partial length recombinant IL-36R protein (amino acids 1-203) was used as the immunogen for this antibody.
-
亚型
- IgG2b
-
-
-
-
应用备注
- WB: 2-4 μg/mL
-
限制
- 仅限研究用
-
-
-
浓度
- 0.5 mg/mL
-
缓冲液
- PBS containing 0.05 % BSA, PH 7.4
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
-
-
- IL1RL2 (Interleukin 1 Receptor-Like 2 (IL1RL2))
-
别名
- IL-36R
-
背景
- IL-36R is a member of the IL-1 receptor family that has been associated with various inflammation-associated diseases. Ligands binding to IL-36R subsequently recruit the IL-1RAcP (IL-1 Receptor Accessory Protein) forming a heterodimeric signaling complex. The latter is also used by IL-1Alpha and IL-1Beta. IL-36R is expressed by different immune cells, including Dendritic Cells, microglia and other myeloid cells. IL-36 stimulation of DC leads to the production of several cytokines by DC, including TNF-a, IL-1, IL-12, and IL-23. This interaction also enhances the expression of MHC class 2 and co-stimulatory molecules.
-
分子量
- 69 kDa
-
基因ID
- 8808
-
UniProt
- Q9HB29
抗原
-