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IFIT2 抗体 (AA 150-370)

IFIT2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5027290
发货至: 中国
  • 抗原 See all IFIT2 抗体
    IFIT2 (Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2))
    抗原表位
    • 15
    • 7
    • 7
    • 6
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    AA 150-370
    适用
    • 45
    • 2
    • 1
    • 1
    宿主
    • 43
    • 2
    克隆类型
    • 45
    多克隆
    标记
    • 17
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IFIT2 antibody is un-conjugated
    应用范围
    • 26
    • 24
    • 13
    • 13
    • 6
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Protein A Chromatography
    免疫原
    A partial length recombinant IFIT2 protein (amino acids 150-370) was used as the immunogen for this antibody.
    亚型
    IgG
    Top Product
    Discover our top product IFIT2 Primary Antibody
  • 应用备注
    WB: 2-4 μg/mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 0.05 % BSA, PH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原
    IFIT2 (Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2))
    别名
    IFIT2 (IFIT2 产品)
    别名
    G10P2 antibody, GARG-39 antibody, IFI-54 antibody, IFI-54K antibody, IFI54 antibody, IFIT-2 antibody, ISG-54 K antibody, ISG-54K antibody, ISG54 antibody, P54 antibody, cig42 antibody, wu:fb58d07 antibody, DKFZp468G198 antibody, AV302338 antibody, Ifi54 antibody, interferon induced protein with tetratricopeptide repeats 2 antibody, interferon-induced protein with tetratricopeptide repeats 2 antibody, interferon-induced protein with tetratricopeptide repeats 15 antibody, IFIT2 antibody, Ifit2 antibody, ifit15 antibody
    背景
    Interferon-induced protein with tetratricopeptide repeats 2 (IFIT2) is one of four related human (ISG56/IFIT1, ISG54/IFIT2, ISG60/IFIT3, ISG58/IFIT5) and three related mouse proteins (Ifit1, Ifit2, Ifit3) characterized by tetratricopeptide motifs. IFIT2 interacts with eukaryotic initiation factor 3 (eIF3)e and eIF3c to inhibit translation. IFIT2 interacts with some AU-rich RNA regions, which seems to be associated with antiviral activity. IFIT2 possesses antiviral activity against corona virus and West Nile virus by acting on the capped viral mRNA and protects from lethal vesicular stomatitis virus neuropathogenesis. Besides the antiviral activity, IFIT2 expression was associated with induction of apoptosis. IFIT2 may alter proinflammatory cytokine response and therefore be involved in the development of septic shock.
    分子量
    54 kDa
    基因ID
    3433
    UniProt
    P09913
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