IFIT2 抗体 (AA 150-370)
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北京 101111
Quick Overview for IFIT2 抗体 (AA 150-370) (ABIN5027290)
抗原
See all IFIT2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 150-370
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纯化方法
- Protein A Chromatography
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免疫原
- A partial length recombinant IFIT2 protein (amino acids 150-370) was used as the immunogen for this antibody.
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亚型
- IgG
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anti-Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2) (AA 130-265) antibody
IFIT2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2) (AA 1-484) antibodyIFIT2 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2) (Internal Region) antibodyIFIT2 适用: 人, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2) (AA 1-484) antibodyIFIT2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2) (AA 273-472) antibodyIFIT2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2) (N-Term) antibodyIFIT2 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 2-4 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- IFIT2 (Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2))
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别名
- IFIT2
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背景
- Interferon-induced protein with tetratricopeptide repeats 2 (IFIT2) is one of four related human (ISG56/IFIT1, ISG54/IFIT2, ISG60/IFIT3, ISG58/IFIT5) and three related mouse proteins (Ifit1, Ifit2, Ifit3) characterized by tetratricopeptide motifs. IFIT2 interacts with eukaryotic initiation factor 3 (eIF3)e and eIF3c to inhibit translation. IFIT2 interacts with some AU-rich RNA regions, which seems to be associated with antiviral activity. IFIT2 possesses antiviral activity against corona virus and West Nile virus by acting on the capped viral mRNA and protects from lethal vesicular stomatitis virus neuropathogenesis. Besides the antiviral activity, IFIT2 expression was associated with induction of apoptosis. IFIT2 may alter proinflammatory cytokine response and therefore be involved in the development of septic shock.
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分子量
- 54 kDa
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基因ID
- 3433
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UniProt
- P09913
抗原
-
