RNF31 抗体 (AA 780-1020)
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北京 101111
Quick Overview for RNF31 抗体 (AA 780-1020) (ABIN5027254)
抗原
See all RNF31 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 780-1020
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纯化方法
- Protein A Chromatography
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免疫原
- A partial length recombinant HOIP/RNF31 protein (amino acids 780-1020) was used as the immunogen for this antibody.
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亚型
- IgG
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应用备注
- WB: 2-4 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- RNF31 (Ring Finger Protein 31 (RNF31))
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别名
- HOIP/RNF31
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背景
- RNF31 (ring finger protein 31), also known as HOIP (HOIL-1-interacting protein) is an atypical E3 ubiquitin ligase that belongs to the RBR (RING-between-RING) family of E3 ligases and is the catalytic component of LUBAC (linear ubiquitin chain assembly complex), a multisubunit E3 ligase. Linear ubiquitin chains are assembled by the LUBAC (Linear Ubiquitin Chain Assembly Complex), which plays a critical role in the activation of the NF-kappaB pathway that is involved in various functions, including cell survival and inflammation. RNF31 is essential for the assembly and function of LUBAC and for various processes governing inflammation and immunity in both hematopoietic and nonhematopoietic cells.
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分子量
- 110 Kda
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基因ID
- 55072
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UniProt
- Q96EP0
抗原
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