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RNF31 抗体 (AA 780-1020)

The 兔 多克隆 anti-RNF31 antibody is suitable to detect RNF31 in samples from 人. It has been validated for WB.
产品编号 ABIN5027254
发货至: 中国
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Quick Overview for RNF31 抗体 (AA 780-1020) (ABIN5027254)

抗原

See all RNF31 抗体
RNF31 (Ring Finger Protein 31 (RNF31))

适用

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宿主

  • 38
  • 1
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克隆类型

  • 40
多克隆

标记

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This RNF31 antibody is un-conjugated

应用范围

  • 35
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Western Blotting (WB)
  • 抗原表位

    • 9
    • 5
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    • 2
    • 1
    • 1
    • 1
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    • 1
    AA 780-1020

    纯化方法

    Protein A Chromatography

    免疫原

    A partial length recombinant HOIP/RNF31 protein (amino acids 780-1020) was used as the immunogen for this antibody.

    亚型

    IgG
  • 应用备注

    WB: 2-4 μg/mL

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS containing 0.05 % BSA, PH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原

    RNF31 (Ring Finger Protein 31 (RNF31))

    别名

    HOIP/RNF31

    背景

    RNF31 (ring finger protein 31), also known as HOIP (HOIL-1-interacting protein) is an atypical E3 ubiquitin ligase that belongs to the RBR (RING-between-RING) family of E3 ligases and is the catalytic component of LUBAC (linear ubiquitin chain assembly complex), a multisubunit E3 ligase. Linear ubiquitin chains are assembled by the LUBAC (Linear Ubiquitin Chain Assembly Complex), which plays a critical role in the activation of the NF-kappaB pathway that is involved in various functions, including cell survival and inflammation. RNF31 is essential for the assembly and function of LUBAC and for various processes governing inflammation and immunity in both hematopoietic and nonhematopoietic cells.

    分子量

    110 Kda

    基因ID

    55072

    UniProt

    Q96EP0
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