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OTUD5 抗体 (AA 300-520)

OTUD5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5027170
发货至: 中国
  • 抗原 See all OTUD5 抗体
    OTUD5 (OTU Domain Containing 5 (OTUD5))
    抗原表位
    • 15
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 300-520
    适用
    • 30
    • 8
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    宿主
    • 29
    • 1
    克隆类型
    • 30
    多克隆
    标记
    • 12
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This OTUD5 antibody is un-conjugated
    应用范围
    • 25
    • 13
    • 13
    • 9
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    交叉反应
    小鼠
    纯化方法
    Protein A Chromatography
    免疫原
    A partial length recombinant DUBA protein (amino acids 300-520) was used as the immunogen for this antibody.
    亚型
    IgG
    Top Product
    Discover our top product OTUD5 Primary Antibody
  • 应用备注
    WB: 2-4 μg/mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 0.05 % BSA, PH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原
    OTUD5 (OTU Domain Containing 5 (OTUD5))
    别名
    DUBA (OTUD5 产品)
    别名
    DUBA antibody, AA407879 antibody, AI553596 antibody, BB114028 antibody, DXImx46e antibody, Sfc7 antibody, otud5 antibody, si:bz30i22.1 antibody, si:rp71-30i22.1 antibody, zgc:154072 antibody, wu:fi28a06 antibody, zgc:100839 antibody, OTU deubiquitinase 5 antibody, OTU domain containing 5 antibody, OTU deubiquitinase 5a antibody, OTU deubiquitinase 5 S homeolog antibody, OTU deubiquitinase 5 L homeolog antibody, OTU deubiquitinase 5b antibody, OTUD5 antibody, Otud5 antibody, otud5a antibody, otud5.S antibody, otud5.L antibody, otud5b antibody
    背景
    DUBA belongs to a subfamily of 14 DUBs characterized by an OTU (Ovarian Tumor) domain. This protein suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. DUBA forms a direct complex with p53 and controls level of ubiquitination. The function of DUBA is required to allow the rapid activation of p53-dependent transcription and a p53-dependent apoptosis in response to DNA damage stress.
    分子量
    62 kDa
    基因ID
    55593
    UniProt
    Q96G74
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