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Desmoglein 3 抗体 (AA 328-526)

DSG3 适用: 人 IHC 宿主: 小鼠 Monoclonal ABM4A31 unconjugated
产品编号 ABIN5027152
发货至: 中国
  • 抗原 See all Desmoglein 3 (DSG3) 抗体
    Desmoglein 3 (DSG3)
    抗原表位
    • 15
    • 8
    • 7
    • 7
    • 7
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 328-526
    适用
    • 66
    • 21
    • 16
    宿主
    • 61
    • 25
    小鼠
    克隆类型
    • 60
    • 26
    单克隆
    标记
    • 35
    • 9
    • 8
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Desmoglein 3 antibody is un-conjugated
    应用范围
    • 64
    • 35
    • 20
    • 17
    • 16
    • 13
    • 13
    • 8
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC)
    纯化方法
    Protein G Chromatography
    免疫原
    A partial length recombinant Desmoglein 3 protein (amino acids 328-526) was used as the immunogen for this antibody.
    克隆位点
    ABM4A31
    亚型
    IgG2b kappa
    Top Product
    Discover our top product DSG3 Primary Antibody
  • 应用备注
    IHC: 1 μg/mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 0.05 % BSA, PH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原
    Desmoglein 3 (DSG3)
    别名
    Desmoglein 3 (DSG3 产品)
    别名
    DSG3 antibody, CDHF6 antibody, PVA antibody, bal antibody, balding antibody, desmoglein 3 antibody, DSG3 antibody, Dsg3 antibody
    背景
    DSG3 (Desmoglein 3) is a calcium-binding transmembrane glycoprotein component of desmosomes, conferring strong cell-cell adhesion. Desmosomes are button-like points of intercellular contact that allow the attachment of cytoskeletal elements to the plasma membrane at sites of cell-cell adhesion. DSG3 is expressed in basal and immediate suprabasal layers of skin. To maintain cell-cell adhesion DSG3 interacts with other desmosomal proteins, such as plakoglobin. Plakoglobin is closely related to Beta-catenin, which is a well-known downstream effector molecule in the canonical Wnt signaling pathway.DSG3 also promotes cancer cell growth and invasion through a plakoglobin-mediated signaling pathway.
    基因ID
    1830
    UniProt
    P32926
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