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Desmoglein 3 抗体 (AA 328-526)

The 小鼠 单克隆 anti-Desmoglein 3 antibody is suitable to detect Desmoglein 3 in samples from 人. It has been validated for IHC.
产品编号 ABIN5027152
发货至: 中国
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Quick Overview for Desmoglein 3 抗体 (AA 328-526) (ABIN5027152)

抗原

See all Desmoglein 3 (DSG3) 抗体
Desmoglein 3 (DSG3)

适用

  • 100
  • 22
  • 16

宿主

  • 67
  • 54
小鼠

克隆类型

  • 64
  • 55
  • 2
单克隆

标记

  • 52
  • 9
  • 9
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Desmoglein 3 antibody is un-conjugated

应用范围

  • 68
  • 37
  • 35
  • 23
  • 20
  • 13
  • 13
  • 13
  • 11
  • 6
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
Immunohistochemistry (IHC)

克隆位点

ABM4A31
  • 抗原表位

    • 23
    • 15
    • 8
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 328-526

    纯化方法

    Protein G Chromatography

    免疫原

    A partial length recombinant Desmoglein 3 protein (amino acids 328-526) was used as the immunogen for this antibody.

    亚型

    IgG2b kappa
  • 应用备注

    IHC: 1 μg/mL

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS containing 0.05 % BSA, PH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原

    Desmoglein 3 (DSG3)

    别名

    Desmoglein 3

    背景

    DSG3 (Desmoglein 3) is a calcium-binding transmembrane glycoprotein component of desmosomes, conferring strong cell-cell adhesion. Desmosomes are button-like points of intercellular contact that allow the attachment of cytoskeletal elements to the plasma membrane at sites of cell-cell adhesion. DSG3 is expressed in basal and immediate suprabasal layers of skin. To maintain cell-cell adhesion DSG3 interacts with other desmosomal proteins, such as plakoglobin. Plakoglobin is closely related to Beta-catenin, which is a well-known downstream effector molecule in the canonical Wnt signaling pathway.DSG3 also promotes cancer cell growth and invasion through a plakoglobin-mediated signaling pathway.

    基因ID

    1830

    UniProt

    P32926
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