CUEDC2 抗体 (AA 100-280)
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Quick Overview for CUEDC2 抗体 (AA 100-280) (ABIN5027122)
抗原
See all CUEDC2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 100-280
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纯化方法
- Protein A Chromatography
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免疫原
- A partial length recombinant CUEDC2 protein (amino acids 100-280) was used as the immunogen for this antibody.
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亚型
- IgG
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应用备注
- WB: 1-2 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- CUEDC2 (CUE Domain Containing 2 (CUEDC2))
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别名
- CUEDC2
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背景
- CUE domain-containing protein 2 commonly known as CUEDC2 is a 32 kDa protein having CUE Domain. It is involved in ubiquitin and proteasome-mediated degradation of progesterone receptor and estrogen receptor. It interacts with PRB isoform of progesterone receptor (PR) and modulates estrogen receptor (ER)-alpha protein stability through the ubiquitin-proteasome pathway. High level expression of CUEDC2 found in breast cancer tissue compared to normal adjacent tissue. It is found that CUEDC2 has some role in regulating IKK dephosphorylation by recruiting PP1.
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分子量
- 30 kDa
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基因ID
- 79004
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UniProt
- Q9H467
抗原
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