OLR1 抗体 (AA 1-200)
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北京 101111
Quick Overview for OLR1 抗体 (AA 1-200) (ABIN5027116)
抗原
See all OLR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-200
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纯化方法
- Protein A Chromatography
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免疫原
- A partial length recombinant CLEC8A protein (amino acids 1-200) was used as the immunogen for this antibody.
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亚型
- IgG
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anti-Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) (AA 201-273) antibody
OLR1 适用: 人, 小鼠, 大鼠, 兔 WB, ELISA, ICC, FACS, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) (AA 51-314) antibodyOLR1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) (AA 57-270) antibodyOLR1 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) (AA 64-92) antibodyOLR1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB21925 unconjugated
anti-Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) (AA 58-273) antibodyOLR1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) (AA 60-312) antibodyOLR1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) (AA 81-273) antibodyOLR1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) (N-Term) antibodyOLR1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) antibody (APC)OLR1 适用: 人 FACS 宿主: 小鼠 Monoclonal 15C4 APC
anti-Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) (AA 1-273) antibodyOLR1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 5-6 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- OLR1 (Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1))
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别名
- CLEC8A/LOX-1/OLR1
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背景
- CLEC8A or OLR1 is a member of C-type lectin super family. It is the receptor that mediates the recognition and degradation of low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in inflammatory responses, pro-oxidative conditions and apoptosis. OLR1 ligation with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, Monocyte adhesion and apoptosis. OLR1 is highly expressed in vascular rich organs, like placenta, liver, lungs and brain. CLEC8A has been reported to be associated with diseases, like atherosclerosis, myocardial infarction and Alzheimer's disease. Alternative splicing produces three isoforms of CLEC8A or OLR1 whose exact function is yet to be ascertained.
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分子量
- 21 kDa (Isoform)
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基因ID
- 4973
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UniProt
- P78380
抗原
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