Calretinin 抗体 (AA 4-238)
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Quick Overview for Calretinin 抗体 (AA 4-238) (ABIN5027071)
抗原
See all Calretinin (CALB2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 4-238
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纯化方法
- Protein A Chromatography
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免疫原
- A partial length recombinant Calretinin protein (amino acids 4-238) was used as the immunogen for this antibody.
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亚型
- IgG
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应用备注
- WB: 1-2 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- Calretinin (CALB2) (Calbindin 2 (CALB2))
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别名
- Calretinin
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背景
- Calretinin is a 29-kD intracellular, vitamin D-dependent calcium binding protein that likely has multiple functional roles including intracellular calcium buffering and message targeting. This protein is a member of the EF-hand family of calcium-binding proteins and first identified in the central nervous system. It has also been identified in a wide variety of non-neural cells, both neoplastic and non-neoplastic. In the oncologic arena calretinin is most commonly used as part of a panel in the separation of pleural mesothelioma from poorly differentiated pulmonary adenocarcinomas. While in most cases highly sensitive and specific for mesothelial origin, calretinin positivity has been reported in carcinomas arising in a myriad of other tissues including ovary, testis, adrenal cortex, colon, breast, sinonasal tract, thymus, skin and even soft tissue.
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分子量
- 31 kDa
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基因ID
- 794
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UniProt
- P22676
抗原
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